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Tapentadol is used to make pain or neuropathic pain associated with diabetic peripheral neuropathy severe enough to require daily, 24-hour, long-term analgesia for which alternative treatment options are inadequate.

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Tapentadol exposes patients and other users to the risks of opioid dependence, abuse and misuse, which can lead to overdose and death. Assess the risk of each patient before prescribing Tapentadol tablets and regularly monitor all patients for the development of this behavior and conditions.

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Not for use as a analgesic. Use only if alternative treatment options (eg, non-opioid analgesics, immediate-release opioids) are ineffective, not tolerated, or otherwise insufficient to provide adequate pain management.

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